Projects
Microfluidic encapsulation of cells!
Our microfluidic platform is capable of high-throughput encapsulation of therapeutic cells. By encapsulating therapeutic cells such as stem cells in certain hydrogels, we can significantly improve cell engraftment and persistence in the targetted tissue. Our microfluidic platforms have been deployed in hospitals to validate their efficacies in producing cell products for in-vivo experimentation.
Cell-Biomaterial interactions!
Novel biomaterials are designed and used to encapsulate cells in order to enhance cell function in certain therapeutic applications. A fundamental understanding of these interactions is allowing us to propose new avenues for improving cell-based therapies.
Independently-addressable array of nanopore sensors integrated in a microfluidic device!
Nanopores are molecular sensors with single-molecule sensitivities. Their integration within microfluidic networks makes it possible to purifiy and pre-concentrate a biomolecular sample prior to analysis with the nanopore.
A device made in our cleanroom, designed to stretch 3D microtissues!
The way cells are stretched when assembled in tissue affects their elastic properties. Shown here are two microstretchers from an array of 50.
The invasiveness of cancer cells is modulated by the dynamics of mechanical stretching!
Our microfluidic device is used to study how cancer cells are excluded from healthy tissue or how they become successful at invading a monolayer of healthy cells depending on mechanical strain.
