NEW FULLY-FUNDED POSITIONS AVAILABLE for students and postdoctoral fellow!
Department of Physics
Ottawa-Carleton Institute for Biomedical Engineering
Department of Mechanical Engineering
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Microfluidic encapsulation of cells! Our microfluidic platform is capable is high-thoughput encapsulation of therapeutic cells. By encapsulating therapeutic cells such as stem cells in certain hydrogels, we can significantly improve cell engraftment and persistence in the targetted tissue. Our microfluidic platforms have been deployed in hospitals to validate their efficacies in producing cell products for in-vivo experimentation.
Cell-Biomaterial interactions! Novel biomaterials are designed and used to encapsulation cells in order to enhance cell function in certain therapeutic applications. A fundamental understanding of these interactions is allowing us to propose new avenues for improving cell-based therapies.
Independently-addressable array of nanopore sensors integrated in a microfluidic device!
Nanopores are molecular sensors with single-molecule sensitivities. Their integration within microfluidic networks makes it possible to purifiy and pre-concentrate a biomolecular sample prior to analysis with the nanopore.
Disease diagnostics with nanopore!
We design DNA-based molecule constructs that allow us to accurately detect disease biomarkers using nanopore sensors. In this example, we demonstrate the detection and quantification of microRNA as a biomarker for cancer.
A device made in our cleanroom, designed to stetch 3D microtissues! The way cells are stretched when assembled in tissue affects their elastic properties. Shown here are two microstretchers out of an array of about 50 more.
The invasiveness of cancer cells is modulated by the dynamics of mechanical stretching! Our microfluidic device is used to study how cancer cells are excluded from healthy tissue or how they become successful at invading a monolayer of healthy cells depending on mechanical strain.
University of Ottawa
150 Louis Pasteur pvt (STM336)
Ottawa, Ontario, Canada, K1N6N5
613-562-5800 ext. 6771 (office) [ext. 7929 (lab)]